Hematopoietic Cell Transplantation for Solid Tumors of Childhood

Hematopoietic Stem Cell Transplantation for Malignant Solid Tumors in Children

The prognosis of malignant solid tumors in children has been improved by multidisciplinary therapy involving surgery, radiotherapy and chemotherapy. High-dose chemotherapy (HDC) followed by autologous (Auto) or allogeneic (Allo) hematopoietic stem cell transplantation (HSCT) has contributed significantly to improvements in the prognosis of high-risk chemosensitive tumors. It has been utilized i...

Feasibility of high-dose iodine-131-metaiodobenzylguanidine therapy for high-risk neuroblastoma preceding myeloablative chemotherapy and hematopoietic stem cell transplantation: a study protocol

Objective(s): High-risk neuroblastoma is a childhood cancer with poorprognosis despite modern multimodality therapy. Internal radiotherapy using131I-metaiodobenzylguanidine (MIBG) is effective for treating the disease even if it isresistant to chemotherapy. The aim of this study is to evaluate the safety and efficacyof 131I-MIBG radiotherapy combined with myeloablative high-dose chemotherapyand...

Medical Policy Hematopoietic Stem Cell Transplantation for Solid Tumors of Childhood

Consolidation treatment for high risk solid tumors in children with myeloablative chemotherapy and autologous hematopoietic progenitor stem cell transplantation

BACKGROUND In childhood cancer, consolidation treatment with chemotherapy followed by autologous hematopoietic progenitor stem cell transplantation is currently an accepted treatment modality in patients with high-risk solid tumors or in patients who have relapsed after conventional treatment. OBJECTIVES The objective of this study was to describe the results of transplantation of a group of ...

Hematopoietic Stem-Cell Transplantation for Solid Tumors of Childhood - 5/26/2017

Hematopoietic stem-cell transplantation (HSCT) refers to a procedure in which hematopoietic stem cells are infused to restore bone marrow function in cancer patients who receive bone-marrowtoxic doses of cytotoxic drugs, with or without whole body radiation therapy. Stem cells may be obtained from the transplant recipient (autologous HSCT) or can be harvested from a donor (allogeneic HSCT). Ste...